Persistent varices in cured patients: Understanding the role of hepatic venous pressure gradient.

ABSTRACT:

Background & aims

Etiologic factor removal (ER) drives recompensation and improves portal hypertension in cirrhosis. Esophageal varices (EV) and portosystemic shunts (PSS) have been found in patients despite hepatic venous pressure gradient (HVPG) dropping below 10 mmHg after ER, questioning HVPG accuracy in reflecting true portal pressure in the setting of ER. We aim to evaluate the correlation of HVPG with direct portal pressure (DPP) in patients with persistence of EV after ER despite HVPG <10 mmHg.

Methods

This is a bicentric 'proof of concept' study evaluating HVPG and ultrasound-guided percutaneous DPP in patients with HCV or alcohol-related cirrhosis with persistent varices and HVPG <10 mmHg after at least 5 years of ER.

Results

Seven patients with HCV and thre

SUBMITTER: Olivas P 

PROVIDER: S-EPMC11489337 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature