Intracranial pressure affects retinal venular complexity in idiopathic intracranial hypertension: a retrospective observational study.

ABSTRACT:

Background

Increased intracranial pressure (ICP) in patients with idiopathic intracranial hypertension (IIH) affects the retinal microvasculature, which can be imaged and quantified by optical coherence tomography angiography (OCTA). We aimed to identify the mediating factor between ICP and OCTA parameters association in IIH patients.

Methods

IIH patients with active intracranial hypertension were enrolled. OCTA imaging was performed after ICP measurement. We quantified the branching complexity of the retinal arterioles and venules from the superficial vascular complex of the OCTA image. Eyes of IIH patients were stratified into eyes with papilledema (IIH-P) and eyes without papilledema (IIH-WP). All participants underwent visual acuity (VA) examination.

Results

One h

SUBMITTER: Cao L 

PROVIDER: S-EPMC11490018 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature