Reliable measures of rest-activity rhythm fragmentation: how many days are needed?

ABSTRACT:

Background

A more fragmented, less stable rest-activity rhythm (RAR) is emerging as a risk factor for health. Accelerometer devices are increasingly used to measure RAR fragmentation using metrics such as inter-daily stability (IS), intradaily variability (IV), transition probabilities (TP), self-similarity parameter (α), and activity balance index (ABI). These metrics were proposed in the context of long period of wear but, in real life, non-wear might introduce measurement bias. This study aims to determine the minimum number of valid days to obtain reliable fragmentation metrics.

Methods

Wrist-worn accelerometer data were drawn from the Whitehall accelerometer sub-study (age: 60 to 83 years) to simulate different non-wear patterns. Pseudo-simulated data with different num

SUBMITTER: Danilevicz IM 

PROVIDER: S-EPMC11490056 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature