Correlation between CT-based phenotypes and serum biomarker in interstitial lung diseases.

ABSTRACT:

Background

The quantitative analysis of computed tomography (CT) and Krebs von den Lungen-6 (KL-6) serum level has gained importance in the diagnosis, monitoring, and prognostication of interstitial lung disease (ILD). However, the associations between quantitative analysis of CT and serum KL-6 level remain poorly understood.

Methods

In this retrospective observational study conducted at tertiary hospital between June 2020 and March 2022, quantitative analysis of CT was performed using the deep learning-based method including reticulation, ground glass opacity (GGO), honeycombing, and consolidation. We investigated the associations between CT-based phenotypes and serum KL-6 measured within three months of the CT scan. Furthermore, we evaluated the performance of the combined

SUBMITTER: Shin B 

PROVIDER: S-EPMC11490112 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature