Individual and joint association of Life's Essential 8 metrics with pre-sarcopenia among U.S. adults.

ABSTRACT:

Background

In recent times, the American Heart Association has updated its approach to evaluating cardiovascular health (CVH) by replacing the previous "Life's Simple 7" with the more demanding "Life's Essential 8" (LE8). However, the impact of enhancing CVH on reducing the risk of pre-sarcopenia and the association of LE8 metrics with pre-sarcopenia remain unexplored.

Methods

LE8 score was calculated among 9857 participants. Multivariable logistic regression was utilized to investigate the associations between LE8 and pre-sarcopenia. Additionally, the weighted quantile sum (WQS) model was employed to determine the combined and individual impact of LE8 metrics on pre-sarcopenia. To assess the indirect effects of peripheral immune responses on the relationships between cardio

SUBMITTER: Lin MS 

PROVIDER: S-EPMC11490172 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature