Parkinson's Disease Progression and Exposure to Contaminated Water at Camp Lejeune.

ABSTRACT:

Background

We recently reported an increased risk of Parkinson's disease (PD) in service members who resided at Marine Base Camp Lejeune, North Carolina, when water supplies were contaminated with trichloroethylene and other volatile organic compounds (VOCs). Prior studies suggest that environmental exposures may affect PD phenotype or progression, but this has not been reported for VOCs.

Objective

The objective of this study was to test whether PD progression is faster in individuals exposed to VOCs in water at Camp Lejeune.

Methods

A cohort of 172,128 marines residing at Camp Lejeune between 1975 and 1985 was previously assembled. We identified individuals with PD in Veterans Health Administration and Medicare databases between 2000 and 2021. Using estimates derived

SUBMITTER: Goldman SM 

PROVIDER: S-EPMC11490380 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature