Assessment of Treatment Sequence in Patients With Stage III Breast Cancer.

ABSTRACT:

Introduction

Stage III breast cancer is defined as locally advanced breast cancer and is treated with curative intent. Historically, overall survival (OS) did not differ based on treatment sequence (neoadjuvant chemotherapy [NAC] followed by surgery versus surgery followed by chemotherapy). Given recent advancements, we examined if treatment sequence may be associated with improved OS in a contemporary cohort of patients with stage III breast cancer.

Methods

Patients aged 18-80 years with prognostic stage III breast cancer who received chemotherapy and surgery were selected from the Surveillance, Epidemiology, and End Results database. Patients were stratified by treatment sequence (NAC versus surgery first). Unadjusted OS and breast cancer-specific survival (BCSS) were esti

SUBMITTER: Ntowe KW 

PROVIDER: S-EPMC11490391 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature