Resting state network changes induced by experimental inaudible infrasound exposure and associations with self-reported noise sensitivity and annoyance.

ABSTRACT: The effects of prolonged infrasound (IS) exposure on brain function and behavior are largely unknown, with only one prior study investigating functional connectivity (FC) changes. In a long-term randomized-controlled trial, 38 participants were exposed to inaudible airborne IS (6 Hz, 80-90 dB) or sham devices for four weeks (8 h/night). We assessed FC changes in resting-state networks (auditory, default mode (DMN), sensorimotor (SMN), and executive control (ECN)), and explored IS 'sensitivity' as a predictor of identified significant FC changes. We also examined correlations between somatic symptoms and FC. IS exposure led to decreased FC in the right precuneus (DMN) and increased FC in the Vermis IV and V (SMN). In the ECN, we observed increased FC in the right frontal middle gyrus (BA8)

SUBMITTER: Forlim CG 

PROVIDER: S-EPMC11490626 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature