Reduced response to regadenoson with increased weight: An artificial intelligence-based quantitative myocardial perfusion study.

ABSTRACT:

Background

There is conflicting evidence regarding the response to a fixed dose of regadenoson in patients with high body weight. The aim of this study was to evaluate the effectiveness of regadenoson in patients with varying body weights using novel quantitative cardiovascular magnetic resonance (CMR) perfusion parameters in addition to standard clinical markers.

Methods

Consecutive patients with typical angina and/or risk factors for coronary artery disease (N = 217) underwent regadenoson stress CMR perfusion imaging using a dual-sequence quantitative protocol with perfusion parameters generated from an artificial intelligence (AI)-based algorithm. CMR was performed on 1.5T scanners using a standard 0.4 mg injection of regadenoson. A cohort of consecutive patients undergoi

SUBMITTER: Androulakis E 

PROVIDER: S-EPMC11490868 | biostudies-literature | 2024 Winter

REPOSITORIES: biostudies-literature