High-frequency irreversible electroporation ablation for the prostate in Beagle dogs.

ABSTRACT:

Background

Ablation procedures have garnered significant attention as a minimally invasive treatment of prostate diseases. However, the feasibility and safety of applying high-frequency irreversible electroporation (H-FIRE) to ablate the Beagle prostate for benign prostatic hyperplasia (BPH) treatment have not been thoroughly explored, the appropriate range of parameters has not been determined. In order to ensure the feasibility and safety of prostate ablation surgery, we conducted a study using Beagle dogs as subjects to investigate prostate tissue.

Methods

We utilized a composite steep pulse therapy device to perform ablations on 26 lateral lobes of the prostate in 13 Beagles, employing various parameters for different needle distances. The effectiveness of this device wa

SUBMITTER: Xing R 

PROVIDER: S-EPMC11491217 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature