Lost opportunities: the underutilization of castrate-resistant prostate cancer treatment in real-world settings.

ABSTRACT:

Background

Various treatment regimens are now available for metastatic castrate-resistant prostate cancer (CRPC). This work evaluates the real-world prescription patterns of CRPC in a large tertiary care center and the factors influencing them.

Methods

Health records of 330 patients with de novo metastatic hormone-sensitive prostate cancer (HSPC), treated and progressed to CRPC between 2016 and 2020, were reviewed from a prospective uro-oncological database. We studied their demographics, medical co-morbidities, treatment utilization patterns before and after progression to CRPC, and survival outcomes.

Results

The median age was 74 years [interquartile range (IQR), 67-80 years] at diagnosis of CRPC. At CRPC, beyond androgen deprivation therapy (ADT) monotherapy

SUBMITTER: Gatsinga R 

PROVIDER: S-EPMC11491230 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature