A narrative review of mitochondrial dysfunction and male infertility.

ABSTRACT:

Background and objective

Recent investigations have highlighted mitochondrial dysfunction as a major component in reduced sperm function and male infertility. The creation of energy, control of reactive oxygen species (ROS), apoptosis, and sperm motility are all critically dependent on mitochondria. The health of the male reproductive system may be significantly impacted by any alteration of mitochondrial structure, function, or integrity. This review intends to open the door to better diagnostic methods, novel therapy strategies, and improved reproductive outcomes for infertile couples by clarifying the crucial function of mitochondria.

Methods

We searched PubMed, Google Scholar, and others for articles related to male infertility and mitochondrial dysfunction from 2014 to

SUBMITTER: Mai Z 

PROVIDER: S-EPMC11491236 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature