The effect of antibiotics on the intestinal microbiota in children - a systematic review.

ABSTRACT:

Background

Children are the age group with the highest exposure to antibiotics (ABX). ABX treatment changes the composition of the intestinal microbiota. The first few years of life are crucial for the establishment of a healthy microbiota and consequently, disturbance of the microbiota during this critical period may have far-reaching consequences. In this review, we summarise studies that have investigated the effect of ABX on the composition of the intestinal microbiota in children.

Methods

According to the PRISMA guidelines, a systematic search was done using MEDLINE and Embase to identify original studies that have investigated the effect of systemic ABX on the composition of the intestinal microbiota in children.

Results

We identified 89 studies investigating a

SUBMITTER: Wurm J 

PROVIDER: S-EPMC11491438 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature