Analysis of safety and efficacy of proton radiotherapy for optic nerve sheath meningioma.

ABSTRACT:

Background

Primary optic nerve sheath meningiomas (ONSMs) represent a group of benign tumors originating from the optic nerve sheath, typically causing painless, gradual onset monocular visual loss, which can result in blindness if left untreated. Radiation therapy represents an important treatment option for patients with ONSM, allowing for preservation and potential improvement in visual function. In particular, proton radiotherapy may enable a reduction of the side effects due to its physical advantage of an inverted dose profile with a steep dose gradient. The study investigates the visual acuity, local tumor control, and treatment-related toxicities following proton beam radiotherapy with a single institutional cohort comprising 32 patients treated for ONSM.

Methods

Pat

SUBMITTER: Deng MY 

PROVIDER: S-EPMC11491494 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature