Association Between Body Mass Index Changes and All-Cause Mortality in Parkinson's Disease.

ABSTRACT:

Background

Whether body weight changes are associated with Parkinson's disease (PD) mortality remains uncertain.

Objective

To investigate the association between changes in body mass index (BMI) and all-cause mortality in patients with PD.

Methods

This nationwide cohort study enrolled 20,703 individuals with new-onset PD (ICD-10 code: G20 and a rare intractable disease registration code: V124) who underwent health screening program by the Korean National Health Insurance Service within two years from pre- and post-PD diagnosis. We identified nine BMI change groups based on three BMI status: underweight (BMI < 18.5 kg/m2), normal or overweight (18.5 kg/m2≤BMI < 25 kg/m2), and obese (BMI≥25 kg/m2).

Results

Of 20,703 individuals, 3,789 (18.0%) died during the foll

SUBMITTER: Yoon SY 

PROVIDER: S-EPMC11492103 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature