Quantifying Diaphragm Blood Flow With Contrast-Enhanced Ultrasound in Humans.

ABSTRACT:

Background

Despite the known interplay between blood flow and function, to our knowledge, there is currently no minimally invasive method to monitor diaphragm hemodynamics. We used contrast-enhanced ultrasound to quantify relative diaphragm blood flow (Q˙_DIA) in humans and assessed the technique's efficacy and reliability during graded inspiratory pressure threshold loading. We hypothesized that: (1) Q˙_DIA would linearly increase with pressure generation, and (2) that there would be good test-retest reliability and interanalyzer reproducibility.

Research question

Can we validate what is, to our knowledge, the first minimally invasive method to measure relative diaphragm blood flow in humans?

Study design and methods

Quantitative contrast-enhanced

SUBMITTER: Bird JD 

PROVIDER: S-EPMC11492223 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature