Establishment of a value assessment framework for orphan medicinal products in China.

ABSTRACT:

Background

This study aimed to establish a suitable value assessment framework for orphan medicinal products in China based on the multi-criteria decision analysis (MCDA) method.

Methods

First, a draft framework of the MCDA criteria was built based on a systematic literature evaluation and the EVIDEM framework tools. Second, stakeholder groups were formed and expert opinions were collected through the brainstorming and expert consultation methods. Third, from the perspective of stakeholders, the five-point weighting method and a two-step percentile distribution method were employed to weigh the quantitative criteria in the framework for orphan drug value evaluation. Meanwhile, from the public perspective, a survey was conducted on a sample of 71 people to obtain the scoring

SUBMITTER: Chen H 

PROVIDER: S-EPMC11492536 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature