Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis.

ABSTRACT: Upper airway (UA) collapsibility is one of the key factors that determine the severity of obstructive sleep apnea (OSA). Interventions for OSA are aimed at reducing UA collapsibility, but selecting the optimal alternative intervention for patients who fail CPAP is challenging because currently no validated method predicts how anatomical changes affect UA collapsibility. The gold standard objective measure of UA collapsibility is the pharyngeal critical pressure (P_crit). A systematic literature review and meta-analysis were performed to identify the anatomical factors with the strongest correlation with P_crit. A search using the PRISMA methodology was performed on PubMed for English language scientific papers that correlated P_crit to anatomic variables and O

SUBMITTER: Hartfield PJ 

PROVIDER: S-EPMC11493082 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature