Safety and efficacy of fecal microbiota transplantation for viral diseases: A systematic review of clinical trials.

ABSTRACT:

Background

Gut microbiota play important roles in several diseases like viral infections. In this systematic review, our objective was to assess the efficacy and safety of fecal microbiota transplantation (FMT) in treating various viral diseases.

Methods

We conducted searches on databases including PubMed, Web of Science, Scopus, and Google Scholar until November 2023. Clinical trials reported outcomes related to safety of FMT or its efficacy in patients with viral diseases were included. We excluded other types of studies that enrolled healthy individuals or patients with other disorders and did not use FMT. The assessment of bias risk was conducted using the National Institutes of Health (NIH) study quality evaluation tool.

Results

Eight studies with total 196 parti

SUBMITTER: Ebrahimi R 

PROVIDER: S-EPMC11493255 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature