Kratom addiction per DSM-5 SUD criteria, and kratom physical dependence: Insights from dosing amount versus frequency.

ABSTRACT:

Background

Kratom products are widely used in the United States, with inadequate understanding of how dosing amounts/frequencies relate to outcomes.

Methods

Between July-November 2022, we enrolled 395 active US adult kratom consumers into a remote study with a baseline survey. We examined self-reported typical dose amounts and frequencies across people and product types, and their associations with outcomes: multiple regression was used to examine whether amounts and frequencies (doses/day) were associated with acute effects, withdrawal symptoms, scores on the Subjective Opioid Withdrawal Scale (SOWS), and addiction (operationalized as DSM-5-based symptoms of kratom-use disorder, KUD).

Results

Participants were 54.9% male, aged 38.1 on average, and 81.3% White. Mean l

SUBMITTER: Rogers JM 

PROVIDER: S-EPMC11493341 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature