New approach methodologies (NAMs) for the <i>in vitro</i> assessment of cleaning products for respiratory irritation: workshop report.

ABSTRACT: The use of in vitro new approach methodologies (NAMs) to assess respiratory irritation depends on several factors, including the specifics of exposure methods and cell/tissue-based test systems. This topic was examined in the context of human health risk assessment for cleaning products at a 1-day public workshop held on 2 March 2023, organized by the American Cleaning Institute^® (ACI). The goals of this workshop were to (1) review in vitro NAMs for evaluation of respiratory irritation, (2) examine different perspectives on current challenges and suggested solutions, and (3) publish a manuscript of the proceedings. Targeted sessions focused on exposure methods, in vitro cell/tissue test systems, and application to human health risk assessment. The importance

SUBMITTER: Haber LT 

PROVIDER: S-EPMC11493779 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature