Effect of severity and etiology of chronic kidney disease in patients with heart failure with mildly reduced ejection fraction.

ABSTRACT:

Objective

The study investigates the prognostic impact of the severity and etiology of chronic kidney disease (CKD) in patients with heart failure with mildly reduced ejection fraction (HFmrEF).

Background

Data regarding the outcomes in patients with CKD in HFmrEF is scarce.

Methods

Consecutive patients with HFmrEF were retrospectively included at one institution from 2016 to 2022. Prognosis of patients with different stages and etiologies of CKD was investigated with regard to the primary endpoint of all-cause mortality at 30 months.

Results

A total of 2155 consecutive patients with HFmrEF were included with an overall prevalence of CKD of 31%. Even milder stages of CKD (i.e., KDIGO stage 3a) were associated with an increased risk of 30-months all-cause mortal

SUBMITTER: Schupp T 

PROVIDER: S-EPMC11493827 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature