Age-related decline in cognitive flexibility and inadequate preparation: evidence from task-state network analysis.

ABSTRACT: Behavioral evidence showed decreased cognitive flexibility in older adults. However, task-based network mechanisms of cognitive flexibility in aging (CFA) remain unclear. Here, we provided the first task-state network evidence that CFA was associated with inadequate preparation for switching trials by revealing age-related changes in functional integration. We examined functional integration in a letter-number switch task that distinguished between the cue and target stages. Both young and older adults showed decreased functional integration from the cue stage to the target stage, indicating that control-related processes were executed as the task progressed. However, compared to young adults, older adults showed less cue-to-target reduction in functional integration, which was primarily d

SUBMITTER: Xia H 

PROVIDER: S-EPMC11493936 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature