ITraNet: a web-based platform for integrated trans-omics network visualization and analysis.

ABSTRACT:

Motivation

Visualization and analysis of biological networks play crucial roles in understanding living systems. Biological networks include diverse types, from gene regulatory networks and protein-protein interactions to metabolic networks. Metabolic networks include substrates, products, and enzymes, which are regulated by allosteric mechanisms and gene expression. However, the analysis of these diverse omics types is challenging due to the diversity of databases and the complexity of network analysis.

Results

We developed iTraNet, a web application that visualizes and analyses trans-omics networks involving four types of networks: gene regulatory networks, protein-protein interactions, metabolic networks, and metabolite exchange networks. Using iTraNet, we found that in w

SUBMITTER: Sugimoto H 

PROVIDER: S-EPMC11493990 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature