Iron Deposition and Functional Connectivity Differences in Females With Migraine Without Aura: A Comparative Study of Headache Sides.

ABSTRACT:

Background

The pathophysiological mechanisms underlying migraine without aura (MwoA) in females remain incompletely elucidated. Currently, the association between headache laterality and iron deposition (ID), and functional connectivity (FC) in female MwoA patients has not been fully studied.

Methods

We prospectively recruited 63 female patients with MwoA and 31 matched healthy controls (HC) from the hospital. ID and FC among the four groups were analyzed using two-sample t-tests (with cluster-wise family-wise error [FWE] correction). Pearson correlation analysis was used to evaluate the relationships between clinical variables and both ID and FC values. Significance level: p < 0.05.

Results

Compared to HC, left-sided MwoA exhibited differences in ID in various brain

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11494401 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature