Trends and predictors of functional class after high-risk left ventricular assist device implantation at a destination therapy center.

ABSTRACT:

Background

Although left ventricular assist device (LVAD) implantation is associated with improved survival, long-term impact on functional class is less well understood in high-risk implants. We undertook this study to better understand how destination therapy (DT) LVAD implantation affects patient functional status and predictors of functional improvement.

Methods

We conducted a single-center, retrospective review of all primary LVAD implantations. Primary outcome was New York Heart Association (NYHA) functional class. An improved sustainable functional improvement was defined as being alive at 1-year with NYHA class I or II symptoms. Multivariable logistic regression was performed to identify predictors of sustainable functional improvement.

Results

From 2017 to 20

SUBMITTER: Eisenga JB 

PROVIDER: S-EPMC11494542 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature