Chronic glycemic control influences the relationship between acute perioperative dysglycemia and perioperative outcome.

ABSTRACT:

Background

The objective of this study was to evaluate the impact of dysglycemia on perioperative outcomes, in patients with and without diabetes, and how prior glycemic control modifies these relationships.

Methods

Consecutive surgical patients admitted to six South Australian tertiary hospitals between 2017 and 2023 were included. Blood glucose levels within 48 h pre- and post-operatively were assessed in an adjusted analyses against a priori selected covariates. Dysglycemia metrics were hyperglycemia (>10.0 mmol/L), hypoglycemia (<4.0 mmol/L), glycemic variability (standard deviation of mean blood glucose >1.7 mmol/L), and stress hyperglycemic ratio (SHR). The primary outcome was hospital mortality.

Results

Of 52 145 patients, 7490 (14.4%) had recognized diabetes.

SUBMITTER: Stretton B 

PROVIDER: S-EPMC11494681 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature