Energy Aware Technology Mapping of Genetic Logic Circuits.

ABSTRACT: Energy and its dissipation are fundamental to all living systems, including cells. Insufficient abundance of energy carriers─as caused by the additional burden of artificial genetic circuits─shifts a cell's priority to survival, also impairing the functionality of the genetic circuit. Moreover, recent works have shown the importance of energy expenditure in information transmission. Despite living organisms being non-equilibrium systems, non-equilibrium models capable of accounting for energy dissipation and non-equilibrium response curves are not yet employed in genetic design automation (GDA) software. To this end, we introduce Energy Aware Technology Mapping, the automated design of genetic logic circuits with respect to energy efficiency and functionality. The basis for this is an ener

SUBMITTER: Kubaczka E 

PROVIDER: S-EPMC11494706 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature