Exploring the vitamin biosynthesis landscape of the human gut microbiota.

ABSTRACT: The human gut microbiota possesses the capacity to synthesize vitamins, especially B group vitamins, which are recognized as indispensable for various biological processes both among members of these bacterial communities and host cells. Accordingly, vitamin production by intestinal commensals has attracted significant interest. Nevertheless, our current understanding of bacterial vitamin synthesis is primarily based on individual genomic and monoculture investigations, therefore not providing an overall view of the biosynthetic potential of complex microbial communities. In the current study, we utilized over 100 bacterial genes known to be involved in the biosynthesis of B group and K vitamins to assess the corresponding vitamin biosynthetic potential of approximately 8,000 human gut mic

SUBMITTER: Tarracchini C 

PROVIDER: S-EPMC11494892 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature