Delivery strategies to improve piglets exposure to oral antimicrobials.

ABSTRACT:

Background

The widespread practice of delivering antimicrobials through drinking water to livestock leads to considerable variability in exposure levels among animals, raising concerns regarding disease outbreaks and the emergence of antimicrobial resistance. This variability is primarily driven by three pivotal factors: fluctuations in drug concentration within water pipes, variances in drinking behavior among animals, and differences in individual pharmacokinetic parameters. The objective of this study is to develop and evaluate a strategy that tailors medication delivery based on the drinking patterns of pigs, aiming to improve medication distribution without increasing the overall dose of medication.

Results

Our results demonstrate that several distribution strategies ba

SUBMITTER: Hernandez N 

PROVIDER: S-EPMC11494959 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature