Significant individual variation in cardiac-cycle-linked cerebrospinal fluid production following subarachnoid hemorrhage.

ABSTRACT:

Background

Spontaneous subarachnoid hemorrhage (SAH) often results in altered cerebrospinal fluid (CSF) flow and secondary hydrocephalus, yet the mechanisms behind these phenomena remain poorly understood. This study aimed to elucidate the impact of SAH on individual CSF flow patterns and their association with secondary hydrocephalus.

Methods

In patients who had experienced SAH, changes in CSF flow were assessed using cardiac-gated phase-contrast magnetic resonance imaging (PC-MRI) at the Sylvian aqueduct and cranio-cervical junction (CCJ). Within these regions of interest, volumetric CSF flow was determined for every pixel and net CSF flow volume and direction calculated. The presence of acute or chronic hydrocephalus was deemed from ventriculomegaly and need of CSF divers

SUBMITTER: Eide PK 

PROVIDER: S-EPMC11495023 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature