Free fatty acids: independent predictors of long-term adverse cardiovascular outcomes in heart failure patients.

ABSTRACT:

Background

The association between plasma free fatty acid (FFA) and the outcomes in the heart failure (HF) patients remains unclear.

Methods

A cohort study among HF patients was performed. Plasma FFA was analyzed as both a continuous and a categorical variable (grouped by tertiles) to assess its association with composite cardiovascular (CV) death and HF hospitalization (CV death & HHP), CV death alone, and all-cause mortality (ACM) using Cox regression models. Subgroup analyses of HF patients with preserved ejection fraction (HFpEF) and mildly reduced/reduced ejection fraction (HFmrEF/HFrEF) were performed. This work also assessed the effectiveness of combining FFA and NT-pro BNP biomarkers for risk stratification by calculating the concordance index (C-index).

Results</

SUBMITTER: Liao GZ 

PROVIDER: S-EPMC11495105 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature