Comparative Safety of Sleeve Gastrectomy and Gastric Bypass: An Instrumental Variables Approach.

ABSTRACT:

Objective

To compare the safety of sleeve gastrectomy and gastric bypass in a large cohort of commercially insured bariatric surgery patients from the IBM MarketScan claims database, while accounting for measurable and unmeasurable sources of selection bias in who is chosen for each operation.

Summary of background data

Sleeve gastrectomy has rapidly become the most common bariatric operation performed in the United States, but its longer-term safety is poorly described, and the risk of worsening gastroesophageal reflux requiring revision may be higher than previously thought. Prior studies comparing sleeve gastrectomy to gastric bypass are limited by low sample size (in randomized trials) and selection bias (in observational studies).

Methods

Instrumental variables a

SUBMITTER: Chhabra KR 

PROVIDER: S-EPMC11495229 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature