Resolving inter-crystal scatter in a light-sharing depth-encoding PET detector.

ABSTRACT: Objective.Inter-crystal scattering (ICS) in light-sharing positron emission tomography (PET) detectors leads to ambiguity in positioning the initial interaction, which significantly degrades the contrast, quantitative accuracy, and spatial resolution of the resulting image. Here, we attempt to resolve the positioning ambiguity of ICS in a light-sharing depth-encoding detector by exploiting the confined, deterministic light-sharing enabled by the segmented light guide unique to Prism-PET.Approach.We first considered a test case of ICS between two adjacent crystals using an analytical and a neural network approach. The analytical approach used a Bayesian estimation framework constructed from a scatter absorption model-the prior-and a detector response model-the likelihood. A si

SUBMITTER: Petersen E 

PROVIDER: S-EPMC11495245 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature