Blood endocan as a biomarker for breast cancer recurrence.

ABSTRACT:

Background

Endocan was reported to affect breast cancer patients negatively and was able to be detected from patients' blood.

Objective

This study aimed to investigate if the measurement of blood endocan in breast cancer patients with high ESM1 expression could be an effective tool to detect postoperative recurrence compared with existing tumor markers.

Methods

Blood was collected before and after the tumor resection from the mouse models of breast cancer, and endocan levels were measured while visualizing metastatic recurrence with noninvasive luminescence imaging. In clinical settings, blood was withdrawn from 16 breast cancer patients before and after the tumor resection, and the effect of lumpectomy on blood endocan level was evaluated. Additionally, the blood end

SUBMITTER: Daiki K 

PROVIDER: S-EPMC11495321 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature