Trans-aconitic acid assimilation system as a widespread bacterial mechanism for environmental adaptation.

ABSTRACT: The ability of bacteria to use natural carbon sources greatly affects their growth and survival in the environment. Bacteria have evolved versatile abilities to use environmental carbon sources, but their diversity and assimilation pathways remain largely unexplored. Trans-aconitic acid (TAA), a geometric isomer of cis-aconitic acid involved in the tricarboxylic acid cycle, has long been considered a natural carbon source metabolizable by bacteria. However, its catabolism and ecological role in linking bacterial interactions with the environment remain unclear. Here, we identify a regulatory system in Bacillus velezensis FZB42 that is capable of sensing and catabolizing TAA. The system consists of a tar operon, an adjacent positive regulatory gene tarR, and a shared promoter. After receivi

SUBMITTER: Zheng C 

PROVIDER: S-EPMC11495376 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature