Predicting success using response after lead implantation with sacral neuromodulation for urgency incontinence.

ABSTRACT:

Importance

Many women report inadequate symptom control after sacral neuromodulation (SNM), despite 50% reduction in urgency incontinence episodes (UUIE) after test stimulation.

Objective

To determine the ideal percent UUIE reduction after test stimulation that predicts 24-month success.

Study design

Using data from a multicenter SNM trial, we constructed receiver operating characteristic curves to identify an ideal threshold of percent UUIE reduction after test stimulation. We defined 24-month success as Patient Global Impression of Improvement of "very much better" to "better." We compared predictive accuracy of two models predicting success: (1) percent UUIE reduction alone and (2) with baseline characteristics.

Results

Of 149 women (median [IQR] baseline da

SUBMITTER: Hendrickson WK 

PROVIDER: S-EPMC11495989 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature