Neural effects of multisensory dance training in Parkinson's disease: evidence from a longitudinal neuroimaging single case study.

ABSTRACT: Dance is associated with beneficial outcomes in motor and non-motor domains in Parkinson's disease (PD) and regular participation may help delay symptom progression in mild PD. However, little is known about the neurobiological mechanisms of dance interventions for PD. The present case study explored potential neuroplastic changes in a 69-year-old male with mild PD participating in regular dance classes over 29 weeks. Functional MRI was performed at four timepoints (pre-training, 11 weeks, 18 weeks, 29 weeks), where the individual imagined a dance choreography while listening to the corresponding music. Neural activity was compared between dance-imagery and fixation blocks at each timepoint. Analysis of functionally defined regions revealed significant blood-oxygen-level-dependent (BOLD) s

SUBMITTER: Simon JR 

PROVIDER: S-EPMC11496053 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature