Modular Fabrication of Microfluidic Graphene FET for Nucleic Acids Biosensing.

ABSTRACT: Graphene field-effect transistors (GFETs) are widely used in biosensing due to their excellent properties in biomolecular signal amplification, exhibiting great potential for high-sensitivity and point-of-care testing in clinical diagnosis. However, difficulties in complicated fabrication steps are the main limitations for the further studies and applications of GFETs. In this study, a modular fabrication technique is introduced to construct microfluidic GFET biosensors within 3 independent steps. The low-melting metal electrodes and intricate flow channels are incorporated to maintain the structural integrity of graphene and facilitate subsequent sensing operations. The as-fabricated GFET biosensor demonstrates excellent long-term stability, and performs effectively in various ion environ

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC11497086 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature