Diverse epistatic effects in barley-powdery mildew interactions localize to host chromosome hotspots.

ABSTRACT: Barley Mildew locus a (Mla) encodes a multi-allelic series of nucleotide-binding leucine-rich repeat (NLR) receptors that specify recognition to diverse cereal diseases. We exploited time-course transcriptome dynamics of barley and derived immune mutants infected with the powdery mildew fungus, Blumeria hordei (Bh), to infer gene effects governed by Mla6 and two other loci significant to disease development, Blufensin1 (Bln1), and Required for Mla6 resistance3 (rar3 = Sgt1 _ΔKL308-309 ). Interactions of Mla6 and Bln1 resulted in diverse epistatic effects on the Bh-induced barley transcriptome, differential immunity to Pseudomonas syringae expressing the effector protease AvrPphB, and

SUBMITTER: Velasquez-Zapata V 

PROVIDER: S-EPMC11497433 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature