The degree of bowel remission predicts phenotype progression in Crohn's disease.

ABSTRACT:

Background

Patients with Crohn's disease (CD) are at risk of progressing from inflammatory to stricturing and penetrating phenotypes. The influence of the depth of remission on the risk of progression has not been adequately evaluated.

Methods

A retrospective cohort study including surgically naïve CD patients with inflammatory phenotype evaluated concomitantly by magnetic resonance enterography and colonoscopy. The degree of remission was correlated with the risk of progressing to stricturing and penetrating phenotypes.

Results

Three hundred nineteen CD patients were included: 27.0% with transmural remission, 16.0% with isolated endoscopic remission, 14.4% with isolated radiologic remission, and 42.6% without remission. Patients with transmural remission presented th

SUBMITTER: Fernandes SR 

PROVIDER: S-EPMC11497657 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature