Educational disparities in brain health and dementia across Latin America and the United States.

ABSTRACT:

Background

Education influences brain health and dementia. However, its impact across regions, specifically Latin America (LA) and the United States (US), is unknown.

Methods

A total of 1412 participants comprising controls, patients with Alzheimer's disease (AD), and frontotemporal lobar degeneration (FTLD) from LA and the US were included. We studied the association of education with brain volume and functional connectivity while controlling for imaging quality and variability, age, sex, total intracranial volume (TIV), and recording type.

Results

Education influenced brain measures, explaining 24%-98% of the geographical differences. The educational disparities between LA and the US were associated with gray matter volume and connectivity variations, especially in

SUBMITTER: Gonzalez-Gomez R 

PROVIDER: S-EPMC11497666 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature