Traumatic brain injury and cognitive change over 30 years among community-dwelling older adults.

ABSTRACT:

Introduction

There is limited evidence regarding the rate of long-term cognitive decline after traumatic brain injury (TBI) among older adults.

Methods

In this prospective cohort study, time-varying TBI was defined by self-report and International Classification of Disease diagnostic codes. Cognitive testing was performed at five visits over 30 years and scores were combined into a global cognition factor score. Adjusted linear mixed-effects models estimated the association of TBI with cognitive change.

Results

A total of 11,701 Atherosclerosis Risk in Communities (ARIC) Study participants (mean baseline age 58 years, 58% female, 25% Black) without TBI at baseline were included. Over follow-up, 18% experienced TBI. The adjusted average decline in cognition per decade

SUBMITTER: Schneider ALC 

PROVIDER: S-EPMC11497669 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature