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Subjective cognitive decline: Memory complaints, cognitive awareness, and metacognition.


ABSTRACT: Cognitive complaints are common in elderly subjects and are a frequent reason for referral to memory clinics. If the complaints are not associated with objective cognitive impairment, the condition is labelled subjective cognitive decline (SCD). SCD is often considered as a stage antedating objective impairment, and an at-risk condition for subsequent dementia. Recent large-scale studies indicate that a significantly increased risk of clinical progression in subjects with SCD is associated with positivity for Alzheimer's disease (AD) biomarkers, a finding supporting the notion that SCD can be due to different mechanisms not associated with neurodegeneration, including functional cognitive disorders. In this paper we present a selective review of research on the relations among SCD, cogniti

SUBMITTER: Cappa SF 

PROVIDER: S-EPMC11497716 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature