Anaerobic benzene oxidation in <i>Geotalea daltonii</i> involves activation by methylation and is regulated by the transition state regulator AbrB.

ABSTRACT: Benzene is a widespread groundwater contaminant that persists under anoxic conditions. The aim of this study was to more accurately investigate anaerobic microbial degradation pathways to predict benzene fate and transport. Preliminary genomic analysis of Geotalea daltonii strain FRC-32, isolated from contaminated groundwater, revealed the presence of putative aromatic-degrading genes. G. daltonii was subsequently shown to conserve energy for growth on benzene as the sole electron donor and fumarate or nitrate as the electron acceptor. The hbs gene, encoding for 3-hydroxybenzylsuccinate synthase (Hbs), a homolog of the radical-forming, toluene-activating benzylsuccinate synthase (Bss), was upregulated during benzene oxidation in G. daltonii, while the bss

SUBMITTER: Bullows JE 

PROVIDER: S-EPMC11497800 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature