Age, period, and cohort effects of Clonorchis sinensis infection prevalence in the Republic of Korea: Insights and projections.

ABSTRACT:

Background

With decades of containment efforts, the prevalence of C. sinensis infection in Korea has shown a declining trend. However, well-tailored intervention assessments remain challenging, particularly when considering the potential impacts of cohort variations in raw freshwater fish consumption behavior, a major transmission route to humans, on this observed decline.

Methodology

We applied an age-period-cohort modeling approach to nationally representative C. sinensis infection prevalence data from 1981-2012 in Korea to assess age, period, and cohort effects on its secular trend and to project the age-stratified prevalence up to 2023.

Principal findings

Our analysis suggests that both cohort and period effects have substantially contributed to the declining prev

SUBMITTER: Jung SM 

PROVIDER: S-EPMC11498711 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature