Responsive Versus Continuous Deep Brain Stimulation for Speech in Essential Tremor: A Pilot Study.

ABSTRACT:

Background

Responsive deep brain stimulation (rDBS) uses physiological signals to deliver stimulation when needed. rDBS is hypothesized to reduce stimulation-induced speech effects associated with continuous DBS (cDBS) in patients with essential tremor (ET).

Objective

To determine if rDBS reduces cDBS speech-related side effects while maintaining tremor suppression.

Methods

Eight ET participants with thalamic DBS underwent unilateral rDBS. Both speech evaluations and tremor severity were assessed across three conditions (DBS OFF, cDBS ON, and rDBS ON). Speech was analyzed using intelligibility ratings. Tremor severity was scored using the Fahn-Tolosa-Marin Tremor Rating Scale (TRS).

Results

During unilateral cDBS, participants experienced reduced speech intelli

SUBMITTER: Cernera S 

PROVIDER: S-EPMC11499032 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature