Association between cardiac time intervals and incident heart failure after acute coronary syndrome.

ABSTRACT:

Background

Cardiac time intervals are sensitive markers of myocardial dysfunction that predispose to heart failure (HF). We aimed to investigate the association between cardiac time intervals and HF in patients with acute coronary syndrome (ACS).

Methods

This study included 386 ACS patients treated with percutaneous coronary intervention (PCI). Patients underwent an echocardiography examination a median of two days after PCI. Cardiac time intervals including isovolumic relaxation time (IVRT), isovolumic contraction time (IVCT), and systolic ejection time (ET), and myocardial performance index (MPI) were obtained by tissue Doppler echocardiography. The outcome was incident HF.

Results

During follow-up (median 4.3, IQR:1.0-6.7 years), 140 (36%) developed HF. In unadjust

SUBMITTER: Bjerregaard CL 

PROVIDER: S-EPMC11499364 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature