Chronic kidney disease and risk of bloodstream infections and sepsis: a 17-year follow-up of the population-based Trondelag Health Study in Norway.

ABSTRACT:

Purpose

Bloodstream infections (BSI) and sepsis are important causes of hospitalization, loss of health, and death globally. Targetable risk factors need to be identified to improve prevention and treatment. In this study, we aimed to evaluate the association of chronic kidney disease (CKD) and risk of and mortality from BSI and sepsis in the general population during a 22-year period.

Methods

We conducted a prospective cohort study among participants in the population-based Norwegian HUNT Study, where 68,438 participated. The median follow-up time was 17.4 years. The exposures were estimated glomerular filtration rate (eGFR) and albumin-creatinine ratio (ACR) in urine. The outcomes were hazard ratios (HR) of hospital admission or death due to BSI or sepsis. The associations

SUBMITTER: Liyanarachi KV 

PROVIDER: S-EPMC11499395 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature