Malaria vaccine efficacy, safety, and community perception in Africa: a scoping review of recent empirical studies.

ABSTRACT:

Aim

The review summarizes the recent empirical evidence on the efficacy, safety, and community perception of malaria vaccines in Africa.

Methods

Academic Search Complete, African Journals Online, CINAHL, Medline, PsychInfo, and two gray literature sources were searched in January 2023, and updated in June 2023. Relevant studies published from 2012 were included. Studies were screened, appraised, and synthesized in line with the review aim. Statistical results are presented as 95% Confidence Intervals and proportions/percentages.

Results

Sixty-six (N = 66) studies met the inclusion criteria. Of the vaccines identified, overall efficacy at 12 months was highest for the R21 vaccine (N = 3) at 77.0%, compared to the RTS,S vaccine (N = 15) at 55%. The efficacy of other vac

SUBMITTER: Chutiyami M 

PROVIDER: S-EPMC11499420 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature